ICSI (Intracytoplasmic Sperm Injection)
Until the 90’s males with very low counts or poor quality sperms had no hope of fathering children, this problem was surmounted by the new breakthrough of ICSI, which took place in Brussels, Belgium in 1992.
In ICSI all the steps are similar to the procedure of IVF, except the step of fertilization. Normally in IVF one egg is mixed with 100,000 sperms and one of the sperms fertilizes the egg on its own, In contrast in ICSI each egg is held and injected with a single live sperm, This micro-Fertilization is done with the help of a machine called the Micromanipulator.ICSI is done where egg is held and injected with single live sperm, cultured for 2-3 days and good quality of embryos are transferred in the uterus.
Indications for ICSI are a technique usually performed in males with:
- Severely low sperm counts
- Poor quality of sperms
- Failed Fertilization in IVF
- Males with azoospermia